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(HGNC name,
Gene symbol,
LocusLink,
Unigene,
RefSeq,
OMIM,
MGI)
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Promolign
provides graphical presentation for SNPs and
transcription factor binding sites in the promoter region of genes
in the context of human-mouse
orthologous sequence alignment.
The goal is to help identify potential regulatory motifs in the upstream sequence of a gene
and to evaluate the function of SNPs in this region.
There are more than 6,400 human-mouse orthologous gene pairs, more than 72,000 homologous blocks,
and more than 100,000 SNPs in the PromoLign database, making it a comprehensive resource for
transcription study at genomic level.
In citing the PromoLign please refer to:
Zhao T, Chang LW, McLeod HL, Stormo GD. PromoLign:
A Database for Upstream Region Analysis and SNPs.
Human Mutation 2004; 23:534-539
♥ Please download and install SVG Viewer plug-in for graphical display.
PromoLign is implemented and maintained by
Dr. Tao Zhao in the laboratory of
Dr. Gary Stormo.
It is supported by
CREATE
network coordinated by
Dr. Howard McLeod,
who is a member of the
NIGMS
sponsored Pharmacogenetics Research Network
(
PGRN).
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© 2003 CREATE network, Washington University School of Medicine.
Disclaimer and Copyright
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